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PANDAS is an acronym for Pediatric Autoimmune Neuropsychiatric Disorders Associated with

Streptococcal infections.

A subset of children with rapid onset of tics have been linked to group A beta-hemolytic streptococcal (GABHS) infections. It is believed that the production of antibodies in response to GABHS is interfering with the function of the basal ganglia. Researches at the National Institute of Mental Health (NIMH) are pursuing the thought that an autoimmune response is being triggered by strep infections.

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